At the IEEE International Electron Devices Meeting (IEDM) 2025, held in San Francisco, imec announced a significant advancement in semiconductor technology. The research and innovation hub successfully demonstrated the first wafer-scale fabrication of solid-state nanopores utilizing extreme ultraviolet (EUV) lithography. This breakthrough could pave the way for more efficient and widespread production of nanopores, which are increasingly recognized for their potential in molecular sensing applications.
The development of solid-state nanopores represents a transformative approach in the field of biosensing. These tiny openings, measuring just a few nanometers in diameter, are capable of detecting individual molecules by measuring changes in ionic current as particles pass through. Despite their promising capabilities, solid-state nanopores have not yet reached commercial viability, primarily due to challenges in scaling production.
Implications for Molecular Sensing
The successful fabrication of nanopores on a wafer scale could significantly reduce manufacturing costs and increase accessibility for various scientific and commercial applications. According to imec, this proof of concept demonstrates that EUV lithography can facilitate the mass production of nanopores, which could lead to their eventual adoption in fields such as healthcare and environmental monitoring.
The capabilities of solid-state nanopores extend beyond simple detection. Researchers anticipate their use for advanced applications, including DNA sequencing and the identification of biomolecules. This versatility could revolutionize diagnostics and enhance our understanding of complex biological systems.
Dr. Gert De 공급>, a leading researcher at imec, emphasized the importance of this achievement, stating, “The ability to fabricate solid-state nanopores at a wafer scale opens new avenues for research and application in molecular sensing. It represents a critical step towards integrating this technology into practical solutions.”
Future Directions and Commercialization
Looking ahead, imec plans to collaborate with industry partners to expedite the transition from laboratory research to commercial products. The integration of solid-state nanopores into existing technologies could create new opportunities in the biosensing market, which is projected to grow substantially over the coming years.
As researchers continue to explore the full potential of these devices, the implications for healthcare, environmental science, and beyond remain vast. The advancements presented at IEDM 2025 mark a pivotal moment in semiconductor research, positioning solid-state nanopores as a cornerstone of future innovations in molecular sensing.
With continued investment and collaboration, the dream of cost-effective, mass-produced solid-state nanopores may soon become a reality, transforming how we detect and analyze molecules in various environments.
